For press already registered to attend the Nobel Lectures in Physiology or Medicine, December 7, Aula Medica, Nobels väg 6, Karolinska Institutet.
Individual accreditations are mandatory for media representatives due to limited space in the media section (registration now closed).
Press badge needed for entrance to the Aula Medica Lecture hall on the 7th of December. The Press badge must be picked up at the Reception Desk, Nobel Forum, Nobels väg 1, between 10:00 and 12:00, December 7th, or on December 6th from 13.00-15.30.
Press are asked to arrive at Aula Medica at the latest 12:00 to have time to set up equipment and be seated in time for the lectures.
Press Conference on December 6th, at 14:00, Nobel Forum, Nobels väg 1
On December 6th, a Press Conference with this year’s Nobel Laureates will be held for media and press representatives only.
Space is limited and individual registration and press accreditions are mandatory.
Nobel Lectures on December 7th, at 13:00, Aula Medica, Nobels väg 6
The official Nobel Lectures held by this year’s Nobel Laureates in Physiology or Medicine are held on December 7th.
For the general public: For the general public there is no registration required and the limited seating are accomodated according to the first come, first served basis. No large bags or camera equipment are allowed in Aula Medica except in the media section. Live bradcasting available at http://www.nobelprize.org and live streaming to a nearby lecture hall.
For press: To get access and seating to the press section you need to register and get press accreditation. Please use the link below to register.
- Large bags or camera equipment not allowed in Aula Medica (except in media section, follow instructions on registration page to be approved permission).
- Individual accreditations are mandatory for media representatives due to limited space in the media section.
- Press are asked to arrive at Aula Medica at the latest 12:00 to have time to set up equipment and be seated in time for the lectures.
- Press badge needed for entrance to the Aula Medica Lecture hall on the 7th of December must be picked up at the Reception Desk, Nobel Forum, Nobels väg 1, between 10:00 and 12:00, December 7th.
Karolinska Research Lectures at NOBEL FORUM
November 5, 16.30, Free admission
Speaker: Huda Y. Zoghbi
Jan and Dan Duncan Neurological Research Institute, at Texas Children’s Hospital, Houston, USA
Lab webpage: https://www.bcm.edu/research/labs/huda-zoghbi
Titel: Lessons in neuronal function from Rett syndrome and related disorders
Rett Syndrome is a fascinating disease for scientists and an unmitigated tragedy for parents: children are apparently healthy for the first year or two after birth, then abruptly—over a matter of weeks—lose acquired motor and cognitive skills, stop speaking, and gradually develop a host of unsettling features such as respiratory dysrhythmias, stereotypic hand-wringing or hand-flapping, constant crying, and seizures. Although the presentation varies widely, the disease seems to affect virtually all brain regions. The genetic basis of this strange disease is loss of function mutations in the X-linked gene MECP2, which encodes Methyl-CpG-binding protein 2 (MeCP2). We have used genetic, behavioral, physiological, anatomical, and molecular approaches to interrogate the pathogenesis of Rett and other disorders involving either loss of MeCP2 function or duplication of the MECP2 region. Although many questions remain unanswered about the precise activities of this protein, one thing is absolutely clear: the brain is exquisitely sensitive to MeCP2 levels. Even modest decreases or modest increases in the protein levels cause neuropsychiatric phenotypes. I will discuss recent work that sheds light on the roles MeCP2 serves in neurons, how it orchestrates an epigenetic program that alters chromatin architecture to influence neuronal network activity and excitatory/inhibitory balance, and the effects of manipulating either MeCP2 levels or the network in animal models.
Host: Sandra Ceccatelli och Tomas Hökfelt, Karolinska Institutet
Contact:Tatiana Goriatcheva, Nobel Office, Nobel Forum,
tel. 524 87805, email@example.com